DLL4 anticorps (AA 423-650)

N° du produit ABIN5027156

Cet anticorps anti-DLL4 est un anticorps Lapin Polyclonal détectant DLL4 dans WB. Adapté pour Humain.

Aperçu rapide pour DLL4 anticorps (AA 423-650) (ABIN5027156)

Antigène: DLL4 (delta-Like 4 (DLL4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DLL4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DLL4 anticorps

Épitope: AA 423-650

Purification: Protein A Chromatography

Immunogène: A partial length recombinant DLL4 protein (amino acids 423-650) was used as the immunogen for this antibody.

Isotype: IgG

Information d'application

Indications d'application: WB: 2-4 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur DLL4

Antigène: DLL4 (delta-Like 4 (DLL4))

Autre désignation: DLL4

Sujet: Dll4 (Delta-like 4), a membrane-bound Notch ligand, plays a fundamental role in vascular development and angiogenesis. It is highly expressed in capillary endothelial tip cells and is involved in suppressing neighboring stalk cells to become tip cells during angiogenesis. Dll4-Notch signaling is mediated either by direct cell-cell contact or by Dll4-containing exosomes from a distance. DLL4 signaling is extensively critical for tumor angiogenesis. Blockage of DLL4 signaling inhibits tumor growth by deregulating angiogenesis and promoting non productive angiogenesis. Additionally, DLL4 has been shown to help regulate the cellular actions of VEGF.

Poids moléculaire: 75 kDa

ID gène: 54567

UniProt: Q9NR61

Pathways: Signalisation Notch