DRAM anticorps (AA 1-230)
Aperçu rapide pour DRAM anticorps (AA 1-230) (ABIN5027168)
Antigène
Voir toutes DRAM (DRAM1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-230
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Purification
- Protein A Chromatography
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Immunogène
- A partial length recombinant DRAM protein (amino acids 1-230) was used as the immunogen for this antibody.
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Isotype
- IgG
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Indications d'application
- WB: 4-6 μg/mL
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- PBS containing 0.05 % BSA, PH 7.4
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- DRAM (DRAM1) (DNA-Damage Regulated Autophagy Modulator 1 (DRAM1))
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Autre désignation
- DRAM
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Sujet
- DRAM (DNA-damage regulated autophagy modulator 1) with a molecular weight of 26 kDa is a lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. It belongs to DRAM/TMEM150 family. This gene is regulated as part of the p53 tumor suppressor pathway. DRAM has a pseudogene on chromosome 4. It is expressed in embryonic tissues and stem cells. DRAM1 is often found to be under-expressed in many tumor types. It has 2 isoforms produced by alternative splicing.
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Poids moléculaire
- 32 kDa
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ID gène
- 55332
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UniProt
- Q8N682
Antigène
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