Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

GAPDH anticorps (AA 120-320)

Cet anticorps Souris Monoclonal détecte spécifiquement GAPDH dans WB et IHC. Il présente une réactivité envers Humain.
N° du produit ABIN5027214

Aperçu rapide pour GAPDH anticorps (AA 120-320) (ABIN5027214)

Antigène

Voir toutes GAPDH Anticorps
GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))

Reactivité

  • 221
  • 153
  • 133
  • 65
  • 47
  • 41
  • 29
  • 26
  • 25
  • 21
  • 19
  • 19
  • 15
  • 15
  • 14
  • 13
  • 12
  • 9
  • 9
  • 6
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Humain

Hôte

  • 168
  • 90
  • 16
  • 9
  • 4
Souris

Clonalité

  • 186
  • 99
Monoclonal

Conjugué

  • 165
  • 31
  • 19
  • 16
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp GAPDH est non-conjugé

Application

  • 232
  • 101
  • 77
  • 75
  • 41
  • 37
  • 36
  • 33
  • 16
  • 15
  • 15
  • 15
  • 7
  • 6
  • 5
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)

Clone

ABM22C5
  • Épitope

    • 36
    • 23
    • 13
    • 12
    • 8
    • 7
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 120-320

     Réactivité croisée

    Souris

    Purification

    Protein G Chromatography

    Immunogène

    A partial length recombinant GAPDH protein (amino acids 120-320) was used as the immunogen for this antibody.

    Isotype

    IgG1 kappa
  • Indications d'application

    WB: 0.5-1 μg/mL, IHC: 5 μg/mL

    Restrictions

    For Research Use only
  • Concentration

    0.5 mg/mL

    Buffer

    PBS containing 0.05 % BSA, PH 7.4

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • Antigène

    GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))

    Autre désignation

    GAPDH

    Sujet

    GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase) is an enzyme best known for its role in glycolysis. However, extra-glycolytic functions of GAPDH have been described, including regulation of protein expression via RNA binding. GAPDH binds to numerous AREs (adenine-uridine rich elements) from various mRNA 3'-untranslated regions in vitro and in vivo despite its lack of a canonical RNA binding motif. GAPDH specifically catalyzes the simultaneous phosphorylation and oxidation of glyceraldehyde 3-phosphate using NAD+ (Nicotinamide Adenine Dinucleotide) as a cofactor to produce glycerate 1,3-biphosphate and NADH. In addition to its role in energy production, GAPDH has been implicated in many cellular processes including DNA repair tRNA export, membrane fusion and transport, endocytosis and nuclear membrane assembly, and cell death.

    Poids moléculaire

    36 kDa

    ID gène

    2597

    UniProt

    P04406
Vous êtes ici:
Chat with us!