GPI anticorps

N° du produit ABIN5027226

Cet anticorps Souris Monoclonal détecte spécifiquement GPI dans WB. Il présente une réactivité envers Sudan ebolavirus.

Aperçu rapide pour GPI anticorps (ABIN5027226)

Antigène: GPI (Glucose-6-Phosphate Isomerase (GPI))

Reactivité: Sudan ebolavirus

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GPI est non-conjugé

Application: Western Blotting (WB)

Clone: ABM47F9

Détail du produit anti-GPI anticorps

Purification: Protein G Chromatography

Immunogène: A partial Length recombinant GP I protein of Sudan Ebola virus was used as an immunogen for this antibody.

Isotype: IgG2b kappa

Information d'application

Indications d'application: WB: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur GPI

Antigène: GPI (Glucose-6-Phosphate Isomerase (GPI))

Autre désignation: GP I

Sujet: The Sudan ebola virus (SUDV) glycoprotein (GP) is an envelope glycoprotein that is present on the virion surface and is involved in receptor binding and mediating viral entry. It is composed of a trimer of heterodimers (GP1/GP2), where GP1 and GP2 remain covalently linked by a disulfide bond9, and the resulting GP1-GP2 pair trimerizes to form a ~450 kDa envelope spike on the viral surface. GP is synthesized as a single polypeptide of 676 amino acids in length that is post-translationally cleaved by furin to yield two subunits, GP1 and GP2. The GP1 subunit contains two heavily glycosylated domains, the glycan cap and the mucin-like domain (MLD). The glycan cap contains only N-linked glycans, whereas the MLD contains both N- and O-linked glycans. All 15 N-glycosylation sites of GP1 could be removed without compromising the expression of GP. In the endosome, a flexible loop containing GP1 residues 190 213 is cleaved by host cathepsins. This cleavage releases the glycan cap and mucin-like domains from GP1. The GP1 subunit is responsible for receptor binding and attachment to new host cells.

Poids moléculaire: 50 kDa

ID gène: 3160774

UniProt: Q7T9D9