MUL1 anticorps (AA 146-352)

N° du produit ABIN5027374

L’anticorps anti-MUL1 Monoclonal Souris est utilisé pour la détection de MUL1 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour MUL1 anticorps (AA 146-352) (ABIN5027374)

Antigène: MUL1 (Mitochondrial E3 Ubiquitin Protein Ligase 1 (MUL1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MUL1 est non-conjugé

Application: Western Blotting (WB)

Clone: ABM4F71

Détail du produit anti-MUL1 anticorps

Épitope: AA 146-352

Purification: Protein G Chromatography

Immunogène: A partial length recombinant MUL1 protein (amino acids 146-352) was used as the immunogen for this antibody.

Isotype: IgG1

Information d'application

Indications d'application: WB: 4-8 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur MUL1

Antigène: MUL1 (Mitochondrial E3 Ubiquitin Protein Ligase 1 (MUL1))

Autre désignation: MUL1

Sujet: MUL1 (Mitochondrial E3 Ubiquitin Protein Ligase-1) is a crucial moderator of RIG-I (Retinoic Acid-Inducible-Gene-I) signaling. This protein is localized to the mitochondria where it interacts with MAVS (Mitochondrial Antiviral Signaling) and catalyzes RIG-I post-translational modifications that inhibit RIG-I-dependent cell signaling. MUL1 contains a unique BAM (Beside A Membrane) domain and a C-terminal RING-finger domain. This protein has been implicated in several processes that occur in animal cells such as NF-KappaB activation, innate immunity and antiviral signaling, suppression of PINK1/parkin defects, mitophagy in skeletal muscle, and caspase-dependent apoptosis.

Poids moléculaire: 40 kDa

ID gène: 79594

UniProt: Q969V5

Pathways: Positive Regulation of Endopeptidase Activity