MUL1 anticorps (AA 146-352)
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- Antigène Voir toutes MUL1 Anticorps
- MUL1 (Mitochondrial E3 Ubiquitin Protein Ligase 1 (MUL1))
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Épitope
- AA 146-352
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp MUL1 est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- Protein G Chromatography
- Immunogène
- A partial length recombinant MUL1 protein (amino acids 146-352) was used as the immunogen for this antibody.
- Clone
- ABM4F71
- Isotype
- IgG1
- Top Product
- Discover our top product MUL1 Anticorps primaire
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- Indications d'application
- WB: 4-8 μg/mL
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- PBS containing 0.05 % BSA, PH 7.4
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- Antigène
- MUL1 (Mitochondrial E3 Ubiquitin Protein Ligase 1 (MUL1))
- Autre désignation
- MUL1 (MUL1 Produits)
- Synonymes
- anticorps C1orf166, anticorps GIDE, anticorps MAPL, anticorps MULAN, anticorps RNF218, anticorps RP11-401M16.2, anticorps mul1, anticorps zgc:92166, anticorps 0610009K11Rik, anticorps AV000801, anticorps Gide, anticorps RGD1309944, anticorps im:7146383, anticorps zgc:165594, anticorps mitochondrial E3 ubiquitin protein ligase 1, anticorps mitochondrial E3 ubiquitin protein ligase 1 L homeolog, anticorps mitochondrial E3 ubiquitin protein ligase 1a, anticorps mitochondrial ubiquitin ligase activator of NFKB 1, anticorps mitochondrial E3 ubiquitin protein ligase 1b, anticorps MUL1, anticorps mul1.L, anticorps mul1a, anticorps Mul1, anticorps mul1b
- Sujet
- MUL1 (Mitochondrial E3 Ubiquitin Protein Ligase-1) is a crucial moderator of RIG-I (Retinoic Acid-Inducible-Gene-I) signaling. This protein is localized to the mitochondria where it interacts with MAVS (Mitochondrial Antiviral Signaling) and catalyzes RIG-I post-translational modifications that inhibit RIG-I-dependent cell signaling. MUL1 contains a unique BAM (Beside A Membrane) domain and a C-terminal RING-finger domain. This protein has been implicated in several processes that occur in animal cells such as NF-KappaB activation, innate immunity and antiviral signaling, suppression of PINK1/parkin defects, mitophagy in skeletal muscle, and caspase-dependent apoptosis.
- Poids moléculaire
- 40 kDa
- ID gène
- 79594
- UniProt
- Q969V5
- Pathways
- Positive Regulation of Endopeptidase Activity
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