POU3F2
Reactivité: Humain, Rat, Souris, Boeuf (Vache)
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
WB: 1-2 μg/mL
Restrictions
For Research Use only
Concentration
0.5 mg/mL
Buffer
PBS containing 0.05 % BSA, PH 7.4
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Antigène
POU3F2
(POU Class 3 Homeobox 2 (POU3F2))
Autre désignation
POU3F2
Sujet
POU3F2 is a developmental neural cell-specific POU domain transcription factor and is crucial for cell lineage determination. In melanoma lesions, cells expressing high levels of POU3F2 show enhanced invasive and metastatic capacity that can in part be explained by repression of MITF (Micropthalmia-associated Transcription Factor) expression via POU3F2 binding to its promoter. POU3F2 is expressed exclusively in the central nervous system, more specifically in postmitotic neurons and glia.