POU3F2 anticorps (AA 220-421)

N° du produit ABIN5027442

Détail du produit anti-POU3F2 anticorps

Antigène: POU3F2 (POU Class 3 Homeobox 2 (POU3F2))

Épitope: AA 220-421

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POU3F2 est non-conjugé

Application: Western Blotting (WB)

Purification: Protein A Chromatography

Immunogène: A partial length recombinant POU3F2 protein (amino acids 220-421) was used as the immunogen for this antibody.

Isotype: IgG

Information d'application

Indications d'application: WB: 1-2 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur POU3F2

Antigène: POU3F2 (POU Class 3 Homeobox 2 (POU3F2))

Autre désignation: POU3F2 (POU3F2 Produits)

Synonymes: anticorps BRN2, anticorps N-Oct3, anticorps OCT7, anticorps OTF-7, anticorps OTF7, anticorps POUF3, anticorps brn-2, anticorps oct-7, anticorps XlPOU3, anticorps pou3f2, anticorps pou3f2-A, anticorps pou3f4, anticorps 9430075J19Rik, anticorps A230098E07Rik, anticorps Brn-2, anticorps Brn2, anticorps Otf7, anticorps XLPOU3b, anticorps pou47, anticorps zp47, anticorps zp47pou, anticorps brn-1.2, anticorps brn1.2, anticorps id:ibd5088, anticorps POU class 3 homeobox 2, anticorps POU class 3 homeobox 2 L homeolog, anticorps POU domain, class 3, transcription factor 2, anticorps POU class 3 homeobox 2 S homeolog, anticorps POU class 3 homeobox 2b, anticorps POU class 3 homeobox 2a, anticorps POU3F2, anticorps pou3f2.L, anticorps Pou3f2, anticorps pou3f2.S, anticorps pou3f2b, anticorps pou3f2a

Sujet: POU3F2 is a developmental neural cell-specific POU domain transcription factor and is crucial for cell lineage determination. In melanoma lesions, cells expressing high levels of POU3F2 show enhanced invasive and metastatic capacity that can in part be explained by repression of MITF (Micropthalmia-associated Transcription Factor) expression via POU3F2 binding to its promoter. POU3F2 is expressed exclusively in the central nervous system, more specifically in postmitotic neurons and glia.

Poids moléculaire: 27 kDa

ID gène: 5454

UniProt: P20265