Dnmt2 anticorps

N° du produit ABIN5027475

Cet anticorps Souris Monoclonal détecte spécifiquement Dnmt2 dans WB et FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Dnmt2 anticorps (ABIN5027475)

Antigène: Dnmt2 (TRDMT1) (tRNA Aspartic Acid Methyltransferase 1 (TRDMT1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Dnmt2 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: ABM1H70

Détail du produit anti-Dnmt2 anticorps

Réactivité croisée: Souris

Purification: Protein G Chromatography

Immunogène: A partial length recombinant protein from DNMT2 was used as the immunogen for this antibody.

Isotype: IgG1 kappa

Information d'application

Indications d'application: WB: 4-6 μg/mL, FACS: 0.5-1 μg/10^6

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur Dnmt2

Antigène: Dnmt2 (TRDMT1) (tRNA Aspartic Acid Methyltransferase 1 (TRDMT1))

Autre désignation: DNMT2

Sujet: DNMT2, also known as tRNA-aspartic acid methyltransferase 1 (TRDMT1), is highly conserved cytosine-C5 methyltransferase that introduces the C38 methylation of tRNAAsp in many species, including lower eukaryotes, plants, insects, and humans. DNMT2 contains all 10 sequence motifs that are conserved among m5C MTases, including the consensus S-adenosyl-L-methionine-binding motifs and the active site ProCys dipeptide. It is a relatively small protein of 391 amino acids and lacks the large N-terminal domains present in the DNMT1 and DNMT3 families. DNMT2 is ubiquitously expressed with multiple mRNA species in most human and mouse adult tissues. It is variably expressed in human cancer cell lines.

Poids moléculaire: 45 kDa

ID gène: 1787

UniProt: Q6ICS7