TOX3 anticorps (AA 232-442)
Aperçu rapide pour TOX3 anticorps (AA 232-442) (ABIN5027585)
Antigène
Voir toutes TOX3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 232-442
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Purification
- Protein G Chromatography
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Immunogène
- A partial length recombinant TOX-3 protein (amino acids 232-442) was used as the immunogen for this antibody
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Isotype
- IgG1 kappa
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Indications d'application
- WB: 2-4 μg/mL, IHC: 5 μg/mL
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- PBS containing 0.05 % BSA, PH 7.4
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- TOX3 (TOX High Mobility Group Box Family Member 3 (TOX3))
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Autre désignation
- TOX-3
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Sujet
- TOX high mobility group box family member 3 (TOX-3) is a member of a subfamily of transcription factors that contains a High Mobility Group box (HMG-box), involved in bending and unwinding of DNA and alteration of chromatin structure. It has two transcript variants encoding different isoforms.TOX3 is expressed in estrogen receptor-positive mammary epithelial cells, including progenitor cells and highly expressed in luminal B breast cancers. Its over expression in human oligodendrocytes reduced cellular death under conditions mimicking Spinal cord injury (SCI).
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Poids moléculaire
- 63 kDa
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ID gène
- 27324
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UniProt
- O15405
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Pathways
- Chromatin Binding
Antigène
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