14-3-3 theta anticorps

N° du produit ABIN5027747

Cet anticorps anti-14-3-3 theta est un anticorps Rat Monoclonal détectant 14-3-3 theta dans WB. Adapté pour Souris.

Aperçu rapide pour 14-3-3 theta anticorps (ABIN5027747)

Antigène: 14-3-3 theta (YWHAQ)

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp 14-3-3 theta est non-conjugé

Application: Western Blotting (WB)

Clone: ABM52H6

Détail du produit anti-14-3-3 theta anticorps

Purification: Protein G Chromatography

Immunogène: Full length recombinant protein of 14-3-3 Theta was used as the immunogen for this antibody.

Isotype: IgG2a kappa

Information d'application

Indications d'application: WB: 2-4 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur 14-3-3 theta

Antigène: 14-3-3 theta (YWHAQ)

Autre désignation: 14-3-3 Theta

Sujet: 14-3-3 Theta, a member of 14-3-3 family, is an adapter protein that plays an important role in a wide range of vital regulatory processes, including signal transduction, apoptosis, cell cycle progression and DNA replication. Humans have seven 14-3-3 isoforms (beta, gamma, epsilon, eta, sigma, theta and zeta) that serve as scaffolds to promote interactions of regulatory phospho-proteins involved in many vital cellular processes. 14-3-3 Theta binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif, resulting in the modulation of the activity of the binding partner except PDPK1, whose kinase activity is negatively regulated. Previous studies have shown that disturbances in native 14-3-3 levels can contribute significantly to the development of various cancers. In lung cancer biopsies, 14-3-3 Theta is found to be present in abundance.

Poids moléculaire: 27 kDa

ID gène: 10971

UniProt: P27348

Pathways: Apoptose, Myometrial Relaxation and Contraction