MHC Class II HLA-DP/DQ/DR anticorps

N° du produit ABIN5067814

Détail du produit anti-MHC Class II HLA-DP/DQ/DR anticorps

Antigène: MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MHC Class II HLA-DP/DQ/DR est non-conjugé

Application: Flow Cytometry (FACS)

Attributs du produit: The clone IVA12 recognizes the shared epitopes of human leucocyte antigen (HLA) class II molecules HLA-DP, HLA-DQ and HLA-DR heterodimeric cell surface glycoproteins comprised of an α (heavy) chain and a β (light) chain. They are expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional antigen presenting cells (APCs). HLA-Class II expressing APCs specifically present antigens recognized by TCR/CD3 complex of CD4+ T cells. Reactive microglia and perivascular cells in multiple sclerosis lesions express all three types of HLA-Class II molecules, whereas microglia in the normal CNS expressed HLA-DR only.

Purification: Purified

Pureté: >95 %

Classe de qualité: GMP Grade

Immunogène: Priess human B cell line

Clone: IVA12

Isotype: IgG1 kappa

Information d'application

Indications d'application: Each lot of this antibody has been pre-titrated and tested by flow cytometric analysis of human PBMCs such that 0.5µg is sufficient for staining 1 million cells in a 100µl staining volume or 100µl of whole blood. It is recommended to titrate antibody reactivity empirically for optimal performance.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur MHC Class II HLA-DP/DQ/DR

Antigène: MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR)

Autre désignation: HLA-DR, DP, DQ (HLA-DP/DQ/DR Produits)

Sujet: The clone IVA12 recognizes the shared epitopes of human leucocyte antigen (HLA) class II molecules HLA-DP, HLA-DQ and HLA-DR heterodimeric cell surface glycoproteins comprised of an α (heavy) chain and a β (light) chain. They are expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional antigen presenting cells (APCs). HLA-Class II expressing APCs specifically present antigens recognized by TCR/CD3 complex of CD4+ T cells. Reactive microglia and perivascular cells in multiple sclerosis lesions express all three types of HLA-Class II molecules, whereas microglia in the normal CNS expressed HLA-DR only.