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HLA-ABC anticorps

GMP Grade HLA-ABC Reactivité: Humain, Babouin, Cynomolgus, Macaque rhésus FACS Hôte: Souris Monoclonal W6-32 unconjugated
N° du produit ABIN5067844
  • Antigène Voir toutes HLA-ABC Anticorps
    HLA-ABC
    Reactivité
    • 71
    • 23
    • 15
    • 13
    • 13
    • 11
    • 11
    • 11
    • 8
    • 7
    • 7
    • 6
    • 1
    • 1
    • 1
    Humain, Babouin, Cynomolgus, Macaque rhésus
    Hôte
    • 60
    • 9
    • 3
    Souris
    Clonalité
    • 62
    • 9
    Monoclonal
    Conjugué
    • 33
    • 8
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HLA-ABC est non-conjugé
    Application
    • 56
    • 19
    • 18
    • 11
    • 10
    • 10
    • 8
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Attributs du produit
    Clone W6/32 recognizes a cell surface 45 kD non-polymorphic epitope protein shared among products of the HLA-A, B, and C loci. HLA class I antigen associated with beta 2-microglobulin are expressed by all human nucleated cells and HLA-Class I down regulation occurs frequently in many cancers which might adversely affect the clinical course of cancer and the outcome of T-cell-based immunotherapy. HLA-Class I present specific foreign antigen to CD8+ T cells which play central role against infection, tumor and also generation of autoimmune diseases.
    Purification
    Purified
    Pureté
    >95 %
    Classe de qualité
    GMP Grade
    Immunogène
    Human Leukocytes
    Clone
    W6-32
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product HLA-ABC Anticorps primaire
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
  • Antigène
    HLA-ABC
    Autre désignation
    HLA-ABC (HLA-ABC Produits)
    Synonymes
    anticorps HLAA, anticorps major histocompatibility complex, class I, A, anticorps HLA-A
    Sujet
    Clone W6/32 recognizes a cell surface 45 kD non-polymorphic epitope protein shared among products of the HLA-A, B, and C loci. HLA class I antigen associated with beta 2-microglobulin are expressed by all human nucleated cells and HLA-Class I down regulation occurs frequently in many cancers which might adversely affect the clinical course of cancer and the outcome of T-cell-based immunotherapy. HLA-Class I present specific foreign antigen to CD8+ T cells which play central role against infection, tumor and also generation of autoimmune diseases.
    Pathways
    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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