HLA-DOA anticorps (N-Term)

N° du produit ABIN5514394

Détail du produit anti-HLA-DOA anticorps

Antigène: HLA-DOA (HLA Class II DO alpha (HLA-DOA))

Épitope: N-Term

Reactivité: Humain, Boeuf (Vache), Cheval, Porc, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HLA-DOA est non-conjugé

Application: Western Blotting (WB)

Séquence: LMTLLSPQEA GATKADHMGS YGPAFYQSYG ASGQFTHEFD EEQLFSVDLK

Homologie: Cow: 83%, Horse: 85%, Human: 100%, Pig: 86%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against DOA. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human DOA

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur HLA-DOA

Antigène: HLA-DOA (HLA Class II DO alpha (HLA-DOA))

Autre désignation: DOA (HLA-DOA Produits)

Synonymes: anticorps HLA-DNA, anticorps HLA-DZA, anticorps HLADZ, anticorps major histocompatibility complex, class II, DO alpha, anticorps HLA-DOA

Sujet: HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level.

Alias Symbols: HLA-DOA, HLA-DNA, HLA-DZA,

Protein Interaction Partner: REL, UBC, HLA-DMA,

Protein Size: 250

ID gène: 3111

NCBI Accession: NP_002110

UniProt: P06340