HLA-DOA anticorps (N-Term)

N° du produit ABIN5514394

L’anticorps anti-HLA-DOA Polyclonal Lapin est utilisé pour la détection de HLA-DOA dans des échantillons de Humain, Rat, Boeuf (Vache), Cheval et Porc. Il a été validé pour WB.

Aperçu rapide pour HLA-DOA anticorps (N-Term) (ABIN5514394)

Antigène: HLA-DOA (HLA Class II DO alpha (HLA-DOA))

Reactivité: Humain, Rat, Boeuf (Vache), Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HLA-DOA est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HLA-DOA anticorps

Épitope: N-Term

Fonction: HLA-DOA Antibody - N-terminal region

Séquence: LMTLLSPQEA GATKADHMGS YGPAFYQSYG ASGQFTHEFD EEQLFSVDLK

Homologie: Cow: 83%, Horse: 85%, Human: 100%, Pig: 86%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against DOA. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human DOA

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65329-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur HLA-DOA

Antigène: HLA-DOA (HLA Class II DO alpha (HLA-DOA))

Autre désignation: HLA-DOA

Sujet:

Background Information: HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level.

Gene Name: major histocompatibility complex, class II, DO alpha

Alternative Symbols: HLADZ, HLA-DNA, HLA-DZA

Protein Name: HLA class II histocompatibility antigen, DO alpha chain

Poids moléculaire: 27kDa

ID gène: 3111

NCBI Accession: NP_002110

UniProt: P06340

Pathways: Human Leukocyte Antigen (HLA) in Adaptive Immune Response