PDE10A anticorps (N-Term)
Aperçu rapide pour PDE10A anticorps (N-Term) (ABIN5514456)
Antigène
Voir toutes PDE10A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- PDE10A Antibody - N-terminal region
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Séquence
- SLHPQVLDEF VSESVSAETV EKWLKRKNNK SEDESAPKEV SRYQDTNMQG
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Homologie
- Dog: 93%, Horse: 93%, Human: 100%, Rabbit: 86%, Rat: 86%
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Attributs du produit
- This is a rabbit polyclonal antibody against PDE10A. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human PDE10A
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP72732-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- PDE10A (phosphodiesterase 10A (PDE10A))
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Autre désignation
- PDE10A
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Sujet
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Background Information: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene.
Alternative Symbols: ADSD2, IOLOD, HSPDE10A, PDE10A19, LINC00473
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Poids moléculaire
- 85kDa
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ID gène
- 10846
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UniProt
- Q9Y233
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Pathways
- cAMP Metabolic Process
Antigène
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