PDE10A anticorps (AA 40-120)

N° du produit ABIN7219164

Cet anticorps Lapin Polyclonal détecte spécifiquement PDE10A dans WB, ELISA et IHC. Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour PDE10A anticorps (AA 40-120) (ABIN7219164)

Antigène: PDE10A (phosphodiesterase 10A (PDE10A))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE10A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-PDE10A anticorps

Épitope: AA 40-120

Fonction: Rabbit Anti-PDE10A Polyclonal Antibody

Specificité: PDE10A Polyclonal Antibody detects endogenous levels of PDE10A protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the N-terminal region of human PDE10A at AA range: 40-120

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PDE10A

Antigène: PDE10A (phosphodiesterase 10A (PDE10A))

Autre désignation: PDE10A

Sujet: PDE10A, cAMP and cAMP-inhibited cGMP 3', 5'-cyclic phosphodiesterase 10AThe phosphodiesterase 10A encoded by PDE10A belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for PDE10A.

Poids moléculaire: 75kD

ID gène: 10846

UniProt: Q9Y233

Pathways: cAMP Metabolic Process