SIRT3 anticorps (N-Term)
Aperçu rapide pour SIRT3 anticorps (N-Term) (ABIN5514670)
Antigène
Voir toutes SIRT3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- AAAPSFFFSS IKGGRRSISF SVGASSVVGS GGSSDKGKLS LQDVAELIRA
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Attributs du produit
- This is a rabbit polyclonal antibody against SIR3. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human SIR3
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SIRT3 (Sirtuin 3 (SIRT3))
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Autre désignation
- SIR3
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Sujet
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This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.
Alias Symbols: SIRT3, SIR2L3,
Protein Interaction Partner: SIRT5, SKP2, UBC, HSPD1, CMYA5, PGAP1, RIF1, NCAPD2, HERC2, TTF2, UQCRH, UGDH, HSP90B1, SNTB1, SBF1, HSPA9, HSPA5, HSPA4, HSPA1L, GRN, ATP5B, ATP5A1, SIRT4, tat, XRCC6, FOXO3, DNM1L, PEX5,
Protein Size: 399 -
ID gène
- 23410
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NCBI Accession
- NP_036371
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UniProt
- Q9NTG7
Antigène
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