SIRT3 anticorps (N-Term)

N° du produit ABIN5514670

L’anticorps anti-SIRT3 Polyclonal Lapin est utilisé pour la détection de SIRT3 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour SIRT3 anticorps (N-Term) (ABIN5514670)

Antigène: SIRT3 (Sirtuin 3 (SIRT3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIRT3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SIRT3 anticorps

Épitope: N-Term

Fonction: SIRT3 Antibody - N-terminal region

Séquence: AAAPSFFFSS IKGGRRSISF SVGASSVVGS GGSSDKGKLS LQDVAELIRA

Attributs du produit: This is a rabbit polyclonal antibody against SIR3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human SIR3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP74220-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur SIRT3

Antigène: SIRT3 (Sirtuin 3 (SIRT3))

Autre désignation: SIRT3

Sujet:

Background Information: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.

Gene Name: sirtuin 3

Alternative Symbols: SIR2L3

Protein Name: NAD-dependent protein deacetylase sirtuin-3, mitochondrial

Poids moléculaire: 43kDa

ID gène: 23410

NCBI Accession: NP_036371

UniProt: Q9NTG7