E2F2 anticorps (Middle Region)

N° du produit ABIN5514732

Cet anticorps Lapin Polyclonal détecte spécifiquement E2F2 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Lapin, Chien, Boeuf (Vache), Cobaye, Poisson zèbre (Danio rerio) et Porc.

Aperçu rapide pour E2F2 anticorps (Middle Region) (ABIN5514732)

Antigène: E2F2 (E2F Transcription Factor 2 (E2F2))

Reactivité: Humain, Souris, Rat, Lapin, Chien, Boeuf (Vache), Cobaye, Poisson zèbre (Danio rerio), Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp E2F2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-E2F2 anticorps

Épitope: Middle Region

Séquence: CSLSFKHLTE DKANKRLAYV TYQDIRAVGN FKEQTVIAVK APPQTRLEVP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 87%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 79%, Rat: 100%, Zebrafish: 75%

Attributs du produit: This is a rabbit polyclonal antibody against E2F2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of Human E2F2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur E2F2

Antigène: E2F2 (E2F Transcription Factor 2 (E2F2))

Autre désignation: E2F2

Sujet: E2F2 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain.

Alias Symbols: E2F-2

Protein Interaction Partner: RB1, GNB5, GIT2, TFDP1, RBL1, ARID3A, ELAVL1, ATAD2, KMT2D, KMT2A, RYBP, SETD8, BCAR1, TFDP2, BRD2, YY1, SP1, CDK3, RNF144A, FHL2, SPIB, RBL2, E2F4, MYBL2, EAPP, TP53BP2, PPP1R13B, TP53INP1, JMY, GAB2, CDC25A, CDC6, E2F1, UXT, MT1G,

Protein Size: 437

ID gène: 1870

NCBI Accession: NM_004091, NP_004082

UniProt: Q14209

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases, DNA Replication