FANCI anticorps (C-Term)

N° du produit ABIN5514761

Cet anticorps anti-FANCI Polyclonal Lapin (ABIN5514761) détecte spécifiquement FANCI dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour FANCI anticorps (C-Term) (ABIN5514761)

Antigène: FANCI (Fanconi Anemia Complementation Group I (FANCI))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FANCI est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FANCI anticorps

Épitope: C-Term

Fonction: FANCI Antibody - C-terminal region

Séquence: MQHMKLSTSR DFKIKGNILD MVLREDGEDE NEEGTASEHG GQNKEPAKKK

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human FANCI

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP73956-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur FANCI

Antigène: FANCI (Fanconi Anemia Complementation Group I (FANCI))

Autre désignation: FANCI

Sujet:

Background Information: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group I. Alternative splicing results in two transcript variants encoding different isoforms.

Gene Name: Fanconi anemia complementation group I

Alternative Symbols: KIAA1794

Protein Name: Fanconi anemia group I protein

Poids moléculaire: 139 kDa

ID gène: 55215

NCBI Accession: NP_001106849

UniProt: Q9NVI1

Pathways: Réparation de l'ADN