GPS2 anticorps (C-Term)

N° du produit ABIN5514785

Détail du produit anti-GPS2 anticorps

Antigène: GPS2 (G Protein Pathway Suppressor 2 (GPS2))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPS2 est non-conjugé

Application: Western Blotting (WB)

Séquence: TAQPPPHYGP TQPAYSPSQQ LRAPSAFPAV QYLSQPQPQP YAVHGHFQPT

Attributs du produit: This is a rabbit polyclonal antibody against GPS2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human GPS2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GPS2

Antigène: GPS2 (G Protein Pathway Suppressor 2 (GPS2))

Autre désignation: GPS2 (GPS2 Produits)

Synonymes: anticorps gps2, anticorps MGC68832, anticorps MGC63588, anticorps zgc:63588, anticorps GPS2, anticorps MGC133909, anticorps amf-1, anticorps AMF-1, anticorps AI505953, anticorps G protein pathway suppressor 2, anticorps G protein pathway suppressor 2 L homeolog, anticorps gps2, anticorps gps2.L, anticorps GPS2, anticorps Gps2

Sujet: This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.

Alias Symbols: GPS2,

Protein Interaction Partner: ATF4, TFIP11, RBPMS, RALBP1, KRT31, SESTD1, NCOR2, HDAC3, SUMO1, UBC, TBL1X, TBL1XR1, vif, MSH5, MSH4, Nr0b2, NR1H4, HNF4A, HDAC1, NR5A2, HDAC5, THRB, THRA, CNOT2, SIN3A, PBK, C19orf57, GPS2, MAP3K7CL, CHD3, SPDL1, SETDB1, CCNA1, EP300, GOLGA2, NCOR1, TP5

Protein Size: 327

ID gène: 2874

NCBI Accession: XP_005256674

UniProt: Q13227