GPS2 anticorps (C-Term)

N° du produit ABIN5514785

Cet anticorps anti-GPS2 Polyclonal Lapin (ABIN5514785) détecte spécifiquement GPS2 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour GPS2 anticorps (C-Term) (ABIN5514785)

Antigène: GPS2 (G Protein Pathway Suppressor 2 (GPS2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPS2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GPS2 anticorps

Épitope: C-Term

Fonction: GPS2 Antibody - C-terminal region

Séquence: TAQPPPHYGP TQPAYSPSQQ LRAPSAFPAV QYLSQPQPQP YAVHGHFQPT

Attributs du produit: This is a rabbit polyclonal antibody against GPS2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human GPS2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP72703-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur GPS2

Antigène: GPS2 (G Protein Pathway Suppressor 2 (GPS2))

Autre désignation: GPS2

Sujet:

Background Information: This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.

Alternative Symbols: AMF-1

Poids moléculaire: 35kDa

ID gène: 2874

NCBI Accession: XP_005256674

UniProt: Q13227