PKM anticorps (C-Term)

N° du produit ABIN5514803

Cet anticorps anti-PKM est un anticorps Lapin Polyclonal détectant PKM dans WB. Adapté pour Humain.

Aperçu rapide pour PKM anticorps (C-Term) (ABIN5514803)

Antigène: PKM (Pyruvate Kinase M1/2 (PKM))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKM est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PKM anticorps

Épitope: C-Term

Séquence: VICATQMLES MIKKPRPTRA EGSDVANAVL DGADCIMLSG ETAKGDYPLE

Attributs du produit: This is a rabbit polyclonal antibody against KPYM. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human KPYM

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PKM

Antigène: PKM (Pyruvate Kinase M1/2 (PKM))

Autre désignation: KPYM

Sujet: This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported.

Alias Symbols: PKM, OIP3, PK2, PK3, PKM2,

Protein Interaction Partner: LNX1, NXT2, HUWE1, ISG15, UBC, POLE2, FUS, SUMO2, SUMO3, STAU1, MDM2, SUZ12, EZH2, IPO11, TWF2, PDLIM5, NPLOC4, PLIN3, UBA2, EIF4A3, ANP32A, SRP14, RAD23B, PPP1CA, PIN1, CTPS1, CBS, CAPZA2, ACAT2, NLK, FBXO6, YWHAQ, RAF1, IGSF8, HDAC6, MAPK7, NPM1, CDK2,

Protein Size: 531

ID gène: 5315

NCBI Accession: XP_005254502

UniProt: P14618

Pathways: L'effet Warburg