HRH1 anticorps (C-Term)

N° du produit ABIN5514867

Cet anticorps Lapin Polyclonal détecte spécifiquement HRH1 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour HRH1 anticorps (C-Term) (ABIN5514867)

Antigène: HRH1 (Histamine Receptor H1 (HRH1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HRH1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HRH1 anticorps

Épitope: C-Term

Fonction: HRH1 Antibody - C-terminal region

Séquence: SSWPSPTEPS SKSGNLRHLH ILIGTSVVKI PFTILLFFLL HRWCSNKKKC

Homologie: Human: 100%

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human HRH1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64611-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur HRH1

Antigène: HRH1 (Histamine Receptor H1 (HRH1))

Autre désignation: HRH1

Sujet:

Background Information: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. It has been associated with multiple processes, including memory and learning, circadian rhythm, and thermoregulation. It is also known to contribute to the pathophysiology of allergic diseases such as atopic dermatitis, asthma, anaphylaxis and allergic rhinitis. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene Name: histamine receptor H1

Alternative Symbols: H1R, H1-R, HH1R, hisH1

Protein Name: histamine H1 receptor

Poids moléculaire: 56 kDa

ID gène: 3269

NCBI Accession: NP_000852

UniProt: P35367

Pathways: Regulation of Carbohydrate Metabolic Process