IL-7 anticorps (C-Term)
Aperçu rapide pour IL-7 anticorps (C-Term) (ABIN5514877)
Antigène
Voir toutes IL-7 (IL7) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- LKVSEGTTIL LNCTGQVKGR KPAALGEAQP TKSLEENKSL KEQKKLNDLC
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Homologie
- Cow: 86%, Dog: 86%, Horse: 93%, Human: 100%, Pig: 100%, Sheep: 93%, Yeast: 85%
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Attributs du produit
- This is a rabbit polyclonal antibody against IL7. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human IL7
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- IL-7 (IL7) (Interleukin 7 (IL7))
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Autre désignation
- IL7
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Sujet
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The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.
Alias Symbols: IL7,
Protein Interaction Partner: CEBPE, APP, IL2RG, IL7R,
Protein Size: 177 -
ID gène
- 3574
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UniProt
- P13232
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Pathways
- Signalistation JAK/STAT
Antigène
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