ITM2B anticorps (N-Term)

N° du produit ABIN5514896

Cet anticorps anti-ITM2B Polyclonal Lapin (ABIN5514896) détecte spécifiquement ITM2B dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour ITM2B anticorps (N-Term) (ABIN5514896)

Antigène: ITM2B (Integral Membrane Protein 2B (ITM2B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITM2B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ITM2B anticorps

Épitope: N-Term

Séquence: FNSALAQKEA KKDEPKSGEE ALIIPPDAVA VDCKDPDDVV PVGQRRAWCW

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ITM2B

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 29 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ITM2B

Antigène: ITM2B (Integral Membrane Protein 2B (ITM2B))

Autre désignation: ITM2B

Sujet: Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia.

Alias Symbols: BRI, FBD, ABRI, BRI2, E25B, E3-16, RDGCA, imBRI2, BRICD2B

Protein Size: 266

ID gène: 9445

NCBI Accession: NM_021999, NP_068839

UniProt: Q9Y287