ITM2B anticorps (N-Term)

N° du produit ABIN5514896

Détail du produit anti-ITM2B anticorps

Antigène: ITM2B (Integral Membrane Protein 2B (ITM2B))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITM2B est non-conjugé

Application: Western Blotting (WB)

Séquence: FNSALAQKEA KKDEPKSGEE ALIIPPDAVA VDCKDPDDVV PVGQRRAWCW

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ITM2B

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 29 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ITM2B

Antigène: ITM2B (Integral Membrane Protein 2B (ITM2B))

Autre désignation: ITM2B (ITM2B Produits)

Synonymes: anticorps ABRI, anticorps BRI, anticorps BRI2, anticorps BRICD2B, anticorps E25B, anticorps E3-16, anticorps FBD, anticorps imBRI2, anticorps AI256040, anticorps Bri, anticorps Bri2, anticorps Bricd2b, anticorps D14Sel6, anticorps E25BMM, anticorps itm2b, anticorps zgc:55770, anticorps zgc:85688, anticorps wu:fc05f02, anticorps MGC52745, anticorps MGC76131, anticorps ITM2B, anticorps itm2bl, anticorps wu:fb94b03, anticorps zgc:64142, anticorps integral membrane protein 2B, anticorps integral membrane protein 2Ba, anticorps integral membrane protein 2B L homeolog, anticorps integral membrane protein 2b, anticorps integral membrane protein 2Bb, anticorps ITM2B, anticorps Itm2b, anticorps itm2ba, anticorps itm2b.L, anticorps itm2b, anticorps itm2bb

Sujet: Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia.

Alias Symbols: BRI, FBD, ABRI, BRI2, E25B, E3-16, RDGCA, imBRI2, BRICD2B

Protein Size: 266

ID gène: 9445

NCBI Accession: NM_021999, NP_068839

UniProt: Q9Y287