MNDA anticorps (Middle Region)

N° du produit ABIN5514973

L’anticorps anti-MNDA Polyclonal Lapin est utilisé pour la détection de MNDA dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour MNDA anticorps (Middle Region) (ABIN5514973)

Antigène: MNDA (Myeloid Cell Nuclear Differentiation Antigen (MNDA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MNDA est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MNDA anticorps

Épitope: Middle Region

Séquence: KRKTPNKEKT EAKRNKVSQE QSKPPGPSGA STSAAVDHPP LPQTSSSTPS

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human MNDA

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MNDA

Antigène: MNDA (Myeloid Cell Nuclear Differentiation Antigen (MNDA))

Autre désignation: MNDA

Sujet: The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons.

Alias Symbols: PYHIN3

Protein Size: 407

ID gène: 4332

NCBI Accession: NM_002432, NP_002423

UniProt: P41218