PDZRN3 anticorps (Middle Region)
Aperçu rapide pour PDZRN3 anticorps (Middle Region) (ABIN5515030)
Antigène
Voir toutes PDZRN3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Fonction
- PDZRN3 Antibody - middle region
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Séquence
- DPYLLPEEHP SAHEYYDPND YIGDIHQEMD REELELEEVD LYRMNSQDKL
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Homologie
- Cow: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 100%, Rat: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against PDZRN3. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of Human PDZRN3
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP43178-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- PDZRN3 (PDZ Domain Containing Ring Finger 3 (PDZRN3))
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Autre désignation
- PDZRN3
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Sujet
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Background Information: PDZRN3 is an E3 ubiquitin-protein ligase. It plays an important role in regulating the surface level of MUSK on myotubes. It mediates the ubiquitination of MUSK, promoting its endocytosis and lysosomal degradation. It might contribute to terminal myogenic differentiation.
Gene Name: PDZ domain containing ring finger 3
Alternative Symbols: LNX3, SEMCAP3, SEMACAP3
Protein Name: E3 ubiquitin-protein ligase PDZRN3
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Poids moléculaire
- 80kDa
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ID gène
- 23024
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UniProt
- Q9UPQ7
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Pathways
- Skeletal Muscle Fiber Development
Antigène
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