Prolactin Receptor anticorps (C-Term)
Aperçu rapide pour Prolactin Receptor anticorps (C-Term) (ABIN5515078)
Antigène
Voir toutes Prolactin Receptor (PRLR) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- DGALSLLPKQ RENSGKPKKP GTPENNKEYA KVSGVMDNNI LVLVPDPHAK
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Purification
- Affinity purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human PRLR
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Prolactin Receptor (PRLR)
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Autre désignation
- PRLR
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Sujet
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This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer.
Alias Symbols: HPRL, MFAB, hPRLrI
Protein Size: 622 -
ID gène
- 5618
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NCBI Accession
- NM_000949, NP_000940
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UniProt
- P16471
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Pathways
- Signalistation JAK/STAT, Response to Growth Hormone Stimulus
Antigène
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