Prolactin Receptor anticorps (Middle Region)

N° du produit ABIN5515079

Cet anticorps anti-Prolactin Receptor Polyclonal Lapin (ABIN5515079) détecte spécifiquement Prolactin Receptor dans WB. L’anticorps est réactif avec des échantillons de Humain, Rat, Souris, Boeuf (Vache), Lapin, Chien, Chévre, Cobaye, Cheval, Mouton et Poisson zèbre (Danio rerio).

Aperçu rapide pour Prolactin Receptor anticorps (Middle Region) (ABIN5515079)

Antigène: Prolactin Receptor (PRLR)

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Lapin, Chien, Chévre, Cobaye, Cheval, Mouton, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Prolactin Receptor est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Prolactin Receptor anticorps

Épitope: Middle Region

Séquence: WAVALKGYSM VTCIFPPVPG PKIKGFDAHL LEKGKSEELL SALGCQDFPP

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PRLR. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of Human PRLR

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Prolactin Receptor

Antigène: Prolactin Receptor (PRLR)

Autre désignation: PRLR

Sujet: This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer.

Alias Symbols: PRLR,

Protein Interaction Partner: UBC, BTRC, STAT5B, PRLR, JAK2, CREBBP, FBXW11, CSH1, PRL, YWHAG, SOCS2, SOCS3, NEK3, CISH, YWHAZ, GHR, TEC, VAV2, ZAP70, PTPN11, VAV1, GH1, PPIA, GTF3A,

Protein Size: 622

ID gène: 5618

UniProt: P16471

Pathways: Signalistation JAK/STAT, Response to Growth Hormone Stimulus