AXIN2 anticorps (C-Term)

N° du produit ABIN5515389

Cet anticorps Lapin Polyclonal détecte spécifiquement AXIN2 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Cobaye, Lapin, Chien, Boeuf (Vache) et Cheval.

Aperçu rapide pour AXIN2 anticorps (C-Term) (ABIN5515389)

Antigène: AXIN2 (Axin 2 (AXIN2))

Reactivité: Humain, Souris, Rat, Cobaye, Lapin, Chien, Boeuf (Vache), Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AXIN2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-AXIN2 anticorps

Épitope: C-Term

Séquence: QWMLESERQS KPKPHSAQST KKAYPLESAR SSPGERASRH HLWGGNSGHP

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against AXIN2. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human AXIN2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur AXIN2

Antigène: AXIN2 (Axin 2 (AXIN2))

Autre désignation: AXIN2

Sujet: AXIN2 is a inhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. It probably facilitate the phosphorylation of beta- catenin and APC by GSK3B (By similarity).

Alias Symbols: AXIN2,

Protein Interaction Partner: FBXW11, GSK3B, GSK3A, UBC, CDC20, AXIN1, KDM5B, ANKRD6, SMAD3, CSNK1E, APC, CTNNB1, APC2, ESR1,

Protein Size: 843

ID gène: 8313

NCBI Accession: NP_004646

UniProt: Q9Y2T1

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling