CYBB anticorps (C-Term)

N° du produit ABIN5515414

L’anticorps Lapin Polyclonal anti-CYBB a été validé pour WB. Il convient pour détecter CYBB dans des échantillons de Humain, Souris, Rat, Lapin, Chien, Boeuf (Vache), Cobaye et Cheval.

Aperçu rapide pour CYBB anticorps (C-Term) (ABIN5515414)

Antigène: CYBB (Cytochrome B-245, beta Polypeptide (CYBB))

Reactivité: Humain, Souris, Rat, Lapin, Chien, Boeuf (Vache), Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYBB est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CYBB anticorps

Épitope: C-Term

Séquence: GRPNWDNEFK TIASQHPNTR IGVFLCGPEA LAETLSKQSI SNSESGPRGV

Homologie: Cow: 85%, Dog: 93%, Guinea Pig: 77%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CYBB. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CYBB

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CYBB

Antigène: CYBB (Cytochrome B-245, beta Polypeptide (CYBB))

Autre désignation: CYBB

Sujet: Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase, neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.

Alias Symbols: AMCBX2, CGD, GP91-1, GP91-PHOX, GP91PHOX, NOX2, p91-PHOX

Protein Interaction Partner: IQGAP1, ACTB, UBC, SUMO1, RAC1, NCF4, NCF2, NCF1, CYBA, ACTG1,

Protein Size: 570

ID gène: 1536

NCBI Accession: NM_000397, NP_000388

UniProt: P04839