IL1A anticorps (N-Term)

N° du produit ABIN5515428

Cet anticorps Lapin Polyclonal détecte spécifiquement IL1A dans WB. Il présente une réactivité envers Humain, Souris, Rat, Chévre et Lapin.

Aperçu rapide pour IL1A anticorps (N-Term) (ABIN5515428)

Antigène: IL1A (Interleukin 1 alpha (IL1A))

Reactivité: Humain, Souris, Rat, Chévre, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL1A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IL1A anticorps

Épitope: N-Term

Séquence: VPDMFEDLKN CYSENEEDSS SIDHLSLNQK SFYHVSYGPL HEGCMDQSVS

Homologie: Goat: 79%, Human: 100%, Mouse: 79%, Rabbit: 79%, Rat: 83%

Attributs du produit: This is a rabbit polyclonal antibody against IL1A. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human IL1A

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur IL1A

Antigène: IL1A (Interleukin 1 alpha (IL1A))

Autre désignation: IL1A

Sujet: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.

Alias Symbols: IL1A, IL1F1,

Protein Size: 271

ID gène: 3552

NCBI Accession: NP_000566

UniProt: P01583

Pathways: Signalisation NF-kappaB, Autophagy, Cancer Immune Checkpoints