IL1A anticorps (N-Term)

N° du produit ABIN5515428

Cet anticorps Lapin Polyclonal détecte spécifiquement IL1A dans WB. Il présente une réactivité avec des échantillons de Humain, Rat, Souris, Chévre et Lapin.

Aperçu rapide pour IL1A anticorps (N-Term) (ABIN5515428)

Antigène: IL1A (Interleukin 1 alpha (IL1A))

Reactivité: Humain, Rat, Souris, Chévre, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL1A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IL1A anticorps

Épitope: N-Term

Fonction: IL1A Antibody - N-terminal region

Séquence: VPDMFEDLKN CYSENEEDSS SIDHLSLNQK SFYHVSYGPL HEGCMDQSVS

Homologie: Goat: 79%, Human: 100%, Mouse: 79%, Rabbit: 79%, Rat: 83%

Attributs du produit: This is a rabbit polyclonal antibody against IL1A. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human IL1A

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54321-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur IL1A

Antigène: IL1A (Interleukin 1 alpha (IL1A))

Autre désignation: IL1A

Sujet:

Background Information: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.

Gene Name: interleukin 1, alpha

Alternative Symbols: IL1, IL-1A, IL1F1, IL1-ALPHA, IL-1 alpha

Protein Name: Interleukin-1 alpha

Poids moléculaire: 29kDa

ID gène: 3552

NCBI Accession: NP_000566

UniProt: P01583

Pathways: Signalisation NF-kappaB, Autophagy, Cancer Immune Checkpoints