CDC14B anticorps (N-Term)

N° du produit ABIN5515888

L’anticorps anti-CDC14B Polyclonal Lapin est utilisé pour la détection de CDC14B dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour CDC14B anticorps (N-Term) (ABIN5515888)

Antigène: CDC14B (CDC14 Cell Division Cycle 14B (CDC14B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDC14B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CDC14B anticorps

Épitope: N-Term

Fonction: CDC14B Antibody - N-terminal region

Séquence: RCSSTSPGVK KIRSSTQQDP RRRDPQDDVY LDITDRLCFA ILYSRPKSAS

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CDC14B

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP80337-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur CDC14B

Antigène: CDC14B (CDC14 Cell Division Cycle 14B (CDC14B))

Autre désignation: CDC14B

Sujet:

Background Information: The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.

Gene Name: cell division cycle 14B

Alternative Symbols: CDC14B3, Cdc14B1, Cdc14B2, hCDC14B

Protein Name: dual specificity protein phosphatase CDC14B

Poids moléculaire: 53 kDa

ID gène: 8555

NCBI Accession: NP_001070649

UniProt: O60729