GNRHR anticorps (C-Term)

N° du produit ABIN5516035

L’anticorps anti-GNRHR Polyclonal Lapin est utilisé pour la détection de GNRHR dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour GNRHR anticorps (C-Term) (ABIN5516035)

Antigène: GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GNRHR est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GNRHR anticorps

Épitope: C-Term

Fonction: GNRHR Antibody - C-terminal region

Séquence: ICNAKIIFTL TRVLHQDPHE LQLNQSKNNI PRARLKTLKM TVAFATSFTV

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human GNRHR

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP79458-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur GNRHR

Antigène: GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))

Autre désignation: GNRHR

Sujet:

Background Information: This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene.

Gene Name: gonadotropin releasing hormone receptor

Alternative Symbols: HH7, GRHR, LRHR, LHRHR, GNRHR1

Protein Name: gonadotropin-releasing hormone receptor

Poids moléculaire: 36 kDa

ID gène: 2798

NCBI Accession: NP_000397

UniProt: P30968