GNRHR anticorps (C-Term)

N° du produit ABIN5516035

L’anticorps anti-GNRHR Polyclonal Lapin est utilisé pour la détection de GNRHR dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour GNRHR anticorps (C-Term) (ABIN5516035)

Antigène: GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GNRHR est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GNRHR anticorps

Épitope: C-Term

Séquence: ICNAKIIFTL TRVLHQDPHE LQLNQSKNNI PRARLKTLKM TVAFATSFTV

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human GNRHR

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GNRHR

Antigène: GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))

Autre désignation: GNRHR

Sujet: This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene.

Alias Symbols: HH7, GRHR, LRHR, LHRHR, GNRHR1

Protein Size: 328

ID gène: 2798

NCBI Accession: NM_000406, NP_000397

UniProt: P30968