INCENP anticorps (C-Term)

N° du produit ABIN5516066

Cet anticorps anti-INCENP Polyclonal Lapin (ABIN5516066) détecte spécifiquement INCENP dans WB. L’anticorps est réactif avec des échantillons de Humain, Rat, Souris, Cheval, Porc et Lapin.

Aperçu rapide pour INCENP anticorps (C-Term) (ABIN5516066)

Antigène: INCENP (Inner Centromere Protein Antigens 135/155kDa (INCENP))

Reactivité: Humain, Rat, Souris, Cheval, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp INCENP est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-INCENP anticorps

Épitope: C-Term

Séquence: RELEEKKKKE EQQRLAERQL QEEQEKKAKE AAGASKALNV TVDVQSPACT

Homologie: Horse: 85%, Human: 100%, Mouse: 86%, Pig: 92%, Rabbit: 92%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against INCENP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human INCENP

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur INCENP

Antigène: INCENP (Inner Centromere Protein Antigens 135/155kDa (INCENP))

Autre désignation: INCENP

Sujet: In mammalian cells, 2 broad groups of centromere-interacting proteins have been described: constitutively binding centromere proteins and 'passenger,' or transiently interacting, proteins (reviewed by Choo, 1997). The constitutive proteins include CENPA, CENPB, CENPC1, and CENPD. The term 'passenger proteins' encompasses a broad collection of proteins that localize to the centromere during specific stages of the cell cycle. These include CENPE, MCAK, KID, cytoplasmic dynein, CliPs, and CENPF/mitosin. The inner centromere proteins (INCENPs), the initial members of the passenger protein group, display a broad localization along chromosomes in the early stages of mitosis but gradually become concentrated at centromeres as the cell cycle progresses into mid-metaphase. During telophase, the proteins are located within the midbody in the intercellular bridge, where they are discarded after cytokinesis

Alias Symbols: INCENP,

Protein Interaction Partner: FLOT1, AURKB, HECW2, AURKC, AURKA, UBC, CDCA8, BIRC5, CBX5, HIST2H3C, SIRT7, Incenp, TUBA1A, EVI5, H2AFZ, SGOL1,

Protein Size: 918

ID gène: 3619

NCBI Accession: NP_064623

UniProt: Q9NQS7

Pathways: Cycle Cellulaire