MERTK anticorps (N-Term)

N° du produit ABIN5516110

L’anticorps anti-MERTK Polyclonal Lapin est utilisé pour la détection de MERTK dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cheval et Porc. Il a été validé pour WB.

Aperçu rapide pour MERTK anticorps (N-Term) (ABIN5516110)

Antigène: MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MERTK est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MERTK anticorps

Épitope: N-Term

Fonction: MERTK Antibody - N-terminal region

Séquence: PEPVNIFWVQ NSSRVNEQPE KSPSVLTVPG LTEMAVFSCE AHNDKGLTVS

Homologie: Cow: 79%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against MERTK. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human MERTK

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59019-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur MERTK

Antigène: MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

Autre désignation: MERTK

Sujet:

Background Information: This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).

Gene Name: c-mer proto-oncogene tyrosine kinase

Alternative Symbols: MER, RP38, c-Eyk, c-mer, Tyro12

Protein Name: Tyrosine-protein kinase Mer

Poids moléculaire: 109kDa

ID gène: 10461

NCBI Accession: NP_006334

UniProt: Q12866

Pathways: Signalisation RTK