TRF1 anticorps (C-Term)

N° du produit ABIN5516265

Cet anticorps Lapin Polyclonal détecte spécifiquement TRF1 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc et Lapin.

Aperçu rapide pour TRF1 anticorps (C-Term) (ABIN5516265)

Antigène: TRF1 (TERF1) (Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRF1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TRF1 anticorps

Épitope: C-Term

Fonction: TERF1 Antibody - C-terminal region

Séquence: NLRSGVRKYG EGNWSKILLH YKFNNRTSVM LKDRWRTMKK LKLISSDSED

Homologie: Cow: 91%, Dog: 91%, Horse: 91%, Human: 100%, Mouse: 90%, Pig: 91%, Rabbit: 82%, Rat: 91%

Attributs du produit: This is a rabbit polyclonal antibody against TERF1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human TERF1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP30358-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur TRF1

Antigène: TRF1 (TERF1) (Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1))

Autre désignation: TERF1

Sujet:

Background Information: This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products.

Gene Name: telomeric repeat binding factor (NIMA-interacting) 1

Alternative Symbols: TRF, PIN2, TRF1, TRBF1, t-TRF1, hTRF1-AS

Protein Name: Telomeric repeat-binding factor 1

Poids moléculaire: 48kDa

ID gène: 7013

NCBI Accession: NP_059523

UniProt: P54274

Pathways: Cycle Cellulaire, Telomere Maintenance, Hormone Transport, Chromatin Binding, Regulation of Cell Size, Positive Regulation of Endopeptidase Activity