GRP78 anticorps (C-Term)
Aperçu rapide pour GRP78 anticorps (C-Term) (ABIN5516335)
Antigène
Voir toutes GRP78 (HSPA5) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- LSSEDKETME KAVEEKIEWL ESHQDADIED FKAKKKELEE IVQPIISKLY
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Homologie
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%
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Attributs du produit
- This is a rabbit polyclonal antibody against GRP78. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human GRP78
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))
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Autre désignation
- GRP78
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Sujet
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The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the ER. As this protein interacts with many ER proteins, it may play a key role in monitoring protein transport through the cell.
Alias Symbols: HSPA5, GRP78,
Protein Interaction Partner: ERLIN2, HUWE1, GPX7, FUS, EP300, AMFR, UBC, RELA, LGALS3BP, AIRE, AURKB, CEP70, CEP76, HAUS2, TUBGCP4, CEP250, MAGED2, TUBGCP2, TUBGCP3, CEP57, TUBG1, TP53, AURKA, SUMO2, SUMO3, CLU, CDKN1A, CDC20, STAU1, SUMO1, NEDD8, MDM2, RPA3, RPA2, RPA1, EED, HSPA1L,
Protein Size: 654 -
ID gène
- 3309
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NCBI Accession
- NP_005338
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UniProt
- P11021
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Pathways
- Thyroid Hormone Synthesis, ER-Nucleus Signaling
Antigène
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