NLRP12 anticorps (N-Term)

N° du produit ABIN5516341

Détail du produit anti-NLRP12 anticorps

Antigène: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP12 est non-conjugé

Application: Western Blotting (WB)

Séquence: LEVSLVTPRK DPQETYRDYV RRKFRLMEDR NARLGECVNL SHRYTRLLLV

Homologie: Cow: 100%, Dog: 90%, Human: 100%, Mouse: 77%, Pig: 100%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against NLRP12. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human NLRP12

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur NLRP12

Antigène: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Autre désignation: NLRP12 (NLRP12 Produits)

Synonymes: anticorps Nalp12, anticorps NALP12, anticorps CLR19.3, anticorps FCAS2, anticorps PAN6, anticorps PYPAF7, anticorps RNO, anticorps RNO2, anticorps NLR family, pyrin domain containing 12, anticorps NLR family pyrin domain containing 12, anticorps NACHT, LRR and PYD domains-containing protein 3, anticorps Nlrp12, anticorps NLRP12, anticorps LOC100018508

Sujet: This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants.

Alias Symbols: NLRP12, NALP12, PYPAF7, RNO,

Protein Interaction Partner: Dlg4, HSP90AA1, HSPA8, HSPA4, FAF1, IRAK1, PYCARD,

Protein Size: 1061

ID gène: 91662

NCBI Accession: NP_653288

UniProt: P59046

Pathways: Positive Regulation of Endopeptidase Activity, Inflammasome