NLRP12 anticorps (N-Term)

N° du produit ABIN5516341

L’anticorps anti-NLRP12 Polyclonal Lapin est utilisé pour la détection de NLRP12 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Porc et Chien. Il a été validé pour WB.

Aperçu rapide pour NLRP12 anticorps (N-Term) (ABIN5516341)

Antigène: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP12 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-NLRP12 anticorps

Épitope: N-Term

Fonction: NLRP12 Antibody - N-terminal region

Séquence: LEVSLVTPRK DPQETYRDYV RRKFRLMEDR NARLGECVNL SHRYTRLLLV

Homologie: Cow: 100%, Dog: 90%, Human: 100%, Mouse: 77%, Pig: 100%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against NLRP12. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human NLRP12

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64968-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur NLRP12

Antigène: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Autre désignation: NLRP12

Sujet:

Background Information: This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants.

Gene Name: NLR family, pyrin domain containing 12

Alternative Symbols: RNO, PAN6, RNO2, FCAS2, NALP12, PYPAF7, CLR19.3

Protein Name: NACHT, LRR and PYD domains-containing protein 12

Poids moléculaire: 116kDa

ID gène: 91662

NCBI Accession: NP_653288

UniProt: P59046

Pathways: Positive Regulation of Endopeptidase Activity, Inflammasome