TUBGCP4 anticorps (C-Term)
Aperçu rapide pour TUBGCP4 anticorps (C-Term) (ABIN5516562)
Antigène
Voir toutes TUBGCP4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Fonction
- TUBGCP4 Antibody - C-terminal region
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Séquence
- KGFSRQSSLL FKILSSVRNH QINSDLAQLL LRLDYNKYYT QAGGTLGSFG
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Attributs du produit
- This is a rabbit polyclonal antibody against GCP4. It was validated on Western Blot.
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Purification
- Affinity purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human GCP4
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP75532-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- TUBGCP4 (Tubulin, gamma Complex Associated Protein 4 (TUBGCP4))
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Autre désignation
- TUBGCP4
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Sujet
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Background Information: This gene encodes a component of the gamma-tubulin ring complex, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants.
Gene Name: tubulin gamma complex associated protein 4
Alternative Symbols: 76P, GCP4, GCP-4, Grip76, MCCRP3
Protein Name: gamma-tubulin complex component 4
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Poids moléculaire
- 73kDa
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ID gène
- 27229
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UniProt
- Q9UGJ1
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Pathways
- M Phase
Antigène
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