ITGB3BP anticorps (N-Term)

N° du produit ABIN5516800

L’anticorps anti-ITGB3BP Polyclonal Lapin est utilisé pour la détection de ITGB3BP dans des échantillons de Humain et Chien. Il a été validé pour WB.

Aperçu rapide pour ITGB3BP anticorps (N-Term) (ABIN5516800)

Antigène: ITGB3BP (Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP))

Reactivité: Humain, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITGB3BP est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ITGB3BP anticorps

Épitope: N-Term

Fonction: ITGB3BP Antibody - N-terminal region

Séquence: QMSLFASPTS SEEQKHRNGL SNEKRKKLNH PSLTESKEST TKDNDEFMML

Homologie: Dog: 91%, Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ITGB3BP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human ITGB3BP

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55000-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur ITGB3BP

Antigène: ITGB3BP (Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP))

Autre désignation: ITGB3BP

Sujet:

Background Information: This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.

Gene Name: integrin beta 3 binding protein (beta3-endonexin)

Alternative Symbols: CENPR, NRIF3, TAP20, CENP-R, HSU37139

Protein Name: Centromere protein R

Poids moléculaire: 23kDa

ID gène: 23421

NCBI Accession: NP_055103

UniProt: Q13352

Pathways: Neurotrophin Signaling Pathway