PSMF1 anticorps (N-Term)

N° du produit ABIN5516829

Cet anticorps Lapin Polyclonal détecte spécifiquement PSMF1 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour PSMF1 anticorps (N-Term) (ABIN5516829)

Antigène: PSMF1 (Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31) (PSMF1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMF1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PSMF1 anticorps

Épitope: N-Term

Séquence: FGLGVGDQPG PNDKKSELLP AGWNNNKDLY VLRYEYKDGS RKLLVKAITV

Attributs du produit: This is a rabbit polyclonal antibody against PSMF1. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PSMF1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PSMF1

Antigène: PSMF1 (Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31) (PSMF1))

Autre désignation: PSMF1

Sujet: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. Alternative transcript variants have been identified for this gene.

Protein Size: 271

ID gène: 9491

NCBI Accession: NP_848693

UniProt: Q92530

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA