F2RL1 anticorps (C-Term)
Aperçu rapide pour F2RL1 anticorps (C-Term) (ABIN5516962)
Antigène
Voir toutes F2RL1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- SAYVLMIRML RSSAMDENSE KKRKRAIKLI VTVLAMYLIC FTPSNLLLVV
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Homologie
- Cow: 79%, Dog: 85%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 86%, Rat: 86%
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Attributs du produit
- This is a rabbit polyclonal antibody against F2RL1. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human F2RL1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- F2RL1 (Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1))
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Autre désignation
- F2RL1
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Sujet
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Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83 % identical to the mouse receptor sequence.
Alias Symbols: GPR11, PAR2
Protein Interaction Partner: BIRC5, COPS5, UBC, Cbl, ST14, GPRASP1, PRTN3, F2, PLG, ELANE, CTSG, CAPN2, CAPN1,
Protein Size: 397 -
ID gène
- 2150
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NCBI Accession
- NM_005242, NP_005233
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UniProt
- P55085
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interactome
Antigène
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