PDE5A anticorps (N-Term)

N° du produit ABIN5517241

L’anticorps anti-PDE5A Polyclonal Lapin est utilisé pour la détection de PDE5A dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour PDE5A anticorps (N-Term) (ABIN5517241)

Antigène: PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE5A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PDE5A anticorps

Épitope: N-Term

Fonction: PDE5A Antibody - N-terminal region

Séquence: MERAGPSFGQ QRQQQQPQQQ KQQQRDQDSV EAWLDDHWDF TFSYFVRKAT

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PDE5A

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP80740-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur PDE5A

Antigène: PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))

Autre désignation: PDE5A

Sujet:

Background Information: This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.

Gene Name: phosphodiesterase 5A

Alternative Symbols: CN5A, PDE5, CGB-PDE

Protein Name: cGMP-specific 3',5'-cyclic phosphodiesterase

Poids moléculaire: 96 kDa

ID gène: 8654

NCBI Accession: NP_001074

UniProt: O76074

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling