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RASGRP1 anticorps (Middle Region)
RASGRP1
Reactivité: Humain
WB
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN5517466
Détail du produit anti-RASGRP1 anticorps
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Antigène
Voir toutes RASGRP1 Anticorps
RASGRP1
(RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1))
Épitope
Tous les épitopes à travers RASGRP1 Anticorps.
Middle Region
Reactivité
Toutes les réactivités sur RASGRP1 Anticorps
Humain
Hôte
Toutes les hôtes sur RASGRP1 Anticorps
Lapin
Clonalité
Toutes les clonalités sur RASGRP1 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers RASGRP1 Anticorps
Cet anticorp RASGRP1 est non-conjugé
Application
Tous les applications à travers RASGRP1 Anticorps.
Western Blotting (WB)
Séquence
GLCHSSISRL KETSSHVPHE INKVLGEMTE LLSSSRNYDN YRRAYGECTD
Purification
Affinity purified
Immunogène
The immunogen is a synthetic peptide directed towards the middle region of human RASGRP1
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Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Détails sur RASGRP1
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Antigène
RASGRP1
(RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1))
Autre désignation
RASGRP1 (RASGRP1 Produits )
Synonymes
anticorps Rasgrp, anticorps CALDAG-GEFI, anticorps CALDAG-GEFII, anticorps RASGRP, anticorps V, anticorps hRasGRP1, anticorps RAS guanyl releasing protein 1, anticorps Rasgrp1, anticorps RASGRP1
Sujet
This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE). Alias Symbols: V, RASGRP, hRasGRP1, CALDAG-GEFI, CALDAG-GEFII Protein Size: 797
ID gène
10125
NCBI Accession
NM_001128602 , NP_001122074
UniProt
O95267
Pathways
TCR Signaling , Fc-epsilon Receptor Signaling Pathway
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