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FAM57A anticorps (C-Term)

Cet anticorps Lapin Polyclonal détecte spécifiquement FAM57A dans WB. Il présente une réactivité envers Humain.
N° du produit ABIN5518053

Aperçu rapide pour FAM57A anticorps (C-Term) (ABIN5518053)

Antigène

FAM57A (Family with Sequence Similarity 57, Member A (FAM57A))

Reactivité

Humain

Hôte

  • 1
Lapin

Clonalité

  • 1
Polyclonal

Conjugué

  • 1
Cet anticorp FAM57A est non-conjugé

Application

Western Blotting (WB)
  • Épitope

    C-Term

    Séquence

    QGLSLLQVPF SIPFYCNVAN AFLVAPQIYW FCLLCRKAVR LFDTPQAKKD

    Purification

    Affinity purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the C terminal region of human FAM57A
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C

    Stockage commentaire

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène

    FAM57A (Family with Sequence Similarity 57, Member A (FAM57A))

    Autre désignation

    FAM57A

    Sujet

    The protein encoded by this gene is a membrane-associated protein that promotes lung carcinogenesis. The encoded protein may be involved in amino acid transport and glutathione metabolism since it can interact with a solute carrier family member (SLC3A2) and an isoform of gamma-glutamyltranspeptidase-like 3. An alternatively spliced variant encoding a protein that lacks a 32 aa internal segment showed the opposite effect, inhibiting lung cancer cell growth. Knockdown of this gene also inhibited lung carcinogenesis and tumor cell growth. Several transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: CT120

    Protein Size: 225

    ID gène

    79850

    NCBI Accession

    NM_024792, NP_079068
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