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NOS2 anticorps (C-Term)

NOS2 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5518782
  • Antigène Voir toutes NOS2 Anticorps
    NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))
    Épitope
    • 16
    • 16
    • 12
    • 10
    • 8
    • 6
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1088-1126, C-Term
    Reactivité
    • 110
    • 74
    • 69
    • 17
    • 2
    • 1
    Humain
    Hôte
    • 127
    • 15
    Lapin
    Clonalité
    • 119
    • 23
    Polyclonal
    Conjugué
    • 74
    • 16
    • 8
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp NOS2 est non-conjugé
    Application
    • 115
    • 45
    • 39
    • 32
    • 28
    • 27
    • 26
    • 19
    • 18
    • 17
    • 8
    • 4
    • 2
    Western Blotting (WB)
    Fonction
    Rabbit IgG polyclonal antibody for Nitric oxide synthase, inducible(NOS2) detection. Tested with WB in Human.
    Séquence
    ARDVAHTLKQ LVAAKLKLNE EQVEDYFFQL KSQKRYHED
    Réactivité croisée (Details)
    No cross reactivity with other proteins.
    Attributs du produit
    Rabbit IgG polyclonal antibody for Nitric oxide synthase, inducible(NOS2) detection. Tested with WB in Human.
    Gene Name: nitric oxide synthase 2, inducible
    Protein Name: Nitric oxide synthase, inducible
    Purification
    Immunogen affinity purified.
    Immunogène
    A synthetic peptide corresponding to a sequence at the C-terminus of human iNOS (1088-1126aa ARDVAHTLKQLVAAKLKLNEEQVEDYFFQLKSQKRYHED), different from the related mouse sequence by five amino acids, and from the related rat sequence by four amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product NOS2 Anticorps primaire
  • Indications d'application
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Liu, Zhang, Han, Wang, Liu, Zhang, Zhou, Xiang: "[Corrigendum] Inhibition of BTK protects lungs from trauma-hemorrhagic shock-induced injury in rats." dans: Molecular medicine reports, Vol. 17, Issue 5, pp. 6926, (2018) (PubMed).

    Sun, Yang, Zhang, Zhao: "Esculentoside A ameliorates cecal ligation and puncture-induced acute kidney injury in rats." dans: Experimental animals, (2017) (PubMed).

    Wang, Chai, He, Ai, Sun, Huang, Li: "Intermittent hypoxia simulating obstructive sleep apnea causes pulmonary inflammation and activates the Nrf2/HO-1 pathway." dans: Experimental and therapeutic medicine, Vol. 14, Issue 4, pp. 3463-3470, (2017) (PubMed).

    Huang, Chen, Wang, Wang, Ning, He, Hu, Yuan, Li, Wang, Liu, Chen, Ren, Sun: "Detecting cell-in-cell structures in human tumor samples by E-cadherin/CD68/CD45 triple staining." dans: Oncotarget, Vol. 6, Issue 24, pp. 20278-87, (2016) (PubMed).

    Lin, Sun, Wang, Zheng, Zhang, Zheng: "Celastrol Ameliorates Ulcerative Colitis-Related Colorectal Cancer in Mice via Suppressing Inflammatory Responses and Epithelial-Mesenchymal Transition." dans: Frontiers in pharmacology, Vol. 6, pp. 320, (2016) (PubMed).

    Dhillon, Mastropaolo, Murchie, Griffiths, Thöni, Elkadri, Xu, Mack, Walters, Guo, Mack, Huynh, Baksh, Silverberg, Brumell, Snapper, Muise: "Higher activity of the inducible nitric oxide synthase contributes to very early onset inflammatory bowel disease." dans: Clinical and translational gastroenterology, Vol. 5, pp. e46, (2014) (PubMed).

    Zhao, Xiong, Mao, Meng, Lei, Li, Deng, Chen, Tu, Lu, Yang, He: "Atmospheric pressure room temperature plasma jets facilitate oxidative and nitrative stress and lead to endoplasmic reticulum stress dependent apoptosis in HepG2 cells." dans: PLoS ONE, Vol. 8, Issue 8, pp. e73665, (2013) (PubMed).

    Long, Yu, Shuai, Guo, Duan, Xu, Li: "The hypoglycemic effect of the kelp on diabetes mellitus model induced by alloxan in rats." dans: International journal of molecular sciences, Vol. 13, Issue 3, pp. 3354-65, (2012) (PubMed).

    Zhang, Wei, Wang, Ding, Wang, Shi: "Cell-specific expression and immunolocalization of nitric oxide synthase isoforms and the related nitric oxide/cyclic GMP signaling pathway in the ovaries of neonatal and immature rats." dans: Journal of Zhejiang University. Science. B, Vol. 12, Issue 1, pp. 55-64, (2011) (PubMed).

    Wang, Du, Wang, Kuang, Wang: "Z-ligustilide attenuates lipopolysaccharide-induced proinflammatory response via inhibiting NF-kappaB pathway in primary rat microglia." dans: Acta pharmacologica Sinica, Vol. 31, Issue 7, pp. 791-7, (2010) (PubMed).

    Wu, Yin, Yao, Haefliger: "Inhibition by brimonidine of forskolin-induced nitric oxide synthase expression in human ciliary bodies in vitro." dans: Molecular vision, Vol. 13, pp. 493-6, (2007) (PubMed).

    Sun, Han, Jia, Jiang, Wang, Zhang, Han, Jiang: "Expressions of inducible nitric oxide synthase and matrix metalloproteinase-9 and their effects on angiogenesis and progression of hepatocellular carcinoma." dans: World journal of gastroenterology, Vol. 11, Issue 38, pp. 5931-7, (2006) (PubMed).

    Wang, Ji, Wang, Gu: "Anti-cancer effect of iNOS inhibitor and its correlation with angiogenesis in gastric cancer." dans: World journal of gastroenterology, Vol. 11, Issue 25, pp. 3830-3, (2005) (PubMed).

    Xu, Deng, Zhu, Lin: "Role of inducible nitric oxide synthase expression in aberrant crypt foci-adenoma-carcinoma sequence." dans: World journal of gastroenterology, Vol. 9, Issue 6, pp. 1246-50, (2003) (PubMed).

    Sassenroth, Trinkmann: "[Implantation of a Binkhorst lens in chronic simple glaucoma]." dans: Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, Vol. 82, Issue 2, pp. 186, (1985) (PubMed).

    Shapiro: "Portrait of a pioneer laryngologist." dans: Eye, ear, nose & throat monthly, Vol. 53, Issue 11, pp. 460-4, (1975) (PubMed).

    Achten: "Diseases of the dermis. General considerations." dans: Archives belges de dermatologie et de syphiligraphie, Vol. 28, Issue 1, pp. 1-13, (1973) (PubMed).

  • Antigène
    NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))
    Autre désignation
    NOS2 (NOS2 Produits)
    Synonymes
    anticorps HEP-NOS, anticorps INOS, anticorps NOS, anticorps NOS2A, anticorps NOS-II, anticorps Nos-2, anticorps Nos2a, anticorps i-NOS, anticorps iNOS, anticorps iNos, anticorps NOS2a, anticorps NOS2, anticorps BmNOS2, anticorps Nsl, anticorps nos2, anticorps nitric oxide synthase 2, anticorps nitric oxide synthase 2, inducible, anticorps inducible nitric oxide synthase, anticorps inducible nitric-oxide synthase, anticorps nanos C2HC-type zinc finger 2, anticorps NOS2, anticorps Nos2, anticorps nos2, anticorps LOC396821, anticorps NANOS2
    Sujet
    Nitric oxide synthase, inducible is an enzyme that in humans is encoded by the NOS2 gene. Nitric oxide (NO) is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter, it is implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. Three different NOS isoforms have been identified which fall into two distinct types, constitutive and inducible. The inducible NOS (iNOS) isoform is expressed in a variety of cell types and tissues in response to inflammatory agents and cytokines. The human iNOS (NOS2) gene is approximately 37 kb in length and consists of 26 exons and 25 introns. NOS2-derived NO is a prerequisite for cytokine signaling and function in innate immunity.

    Synonyms: Ascites | HEP NOS | Hepatocyte NOS | HEPNOS | HEP-NOS | Inducible NOS | iNOS | NANOS2 | nitric oxide synthase 2, inducible | NOS 2A | NOS2A | P60321
    ID gène
    4843
    UniProt
    P35228
    Pathways
    Retinoic Acid Receptor Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Inositol Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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