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BRMS1 anticorps (AA 52-244)

Cet anticorps anti-BRMS1 est un anticorps Lapin Polyclonal détectant BRMS1 dans WB. Adapté pour Humain, Souris et Rat.
N° du produit ABIN5518814

Aperçu rapide pour BRMS1 anticorps (AA 52-244) (ABIN5518814)

Antigène

Voir toutes BRMS1 Anticorps
BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))

Reactivité

  • 50
  • 24
  • 23
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Humain, Souris, Rat

Hôte

  • 48
  • 2
Lapin

Clonalité

  • 46
  • 4
Polyclonal

Conjugué

  • 24
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp BRMS1 est non-conjugé

Application

  • 43
  • 17
  • 13
  • 13
  • 6
  • 5
  • 4
  • 4
  • 4
  • 3
Western Blotting (WB)
  • Épitope

    • 15
    • 8
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 52-244

    Fonction

    Anti-BRMS1 Antibody Picoband®

    Réactivité croisée (Details)

    No cross-reactivity with other proteins.

    Attributs du produit

    Anti-BRMS1 Antibody Picoband® (ABIN5518814). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Purification

    Immunogen affinity purified.

    Immunogène

    E.coli-derived human BRMS1 recombinant protein (Position: D52-D244). Human BRMS1 shares 93.6% and 96% amino acid (aa) sequence identity with mouse and rat BRMS1, respectively.

    Isotype

    IgG
  • Indications d'application

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    1. Seraj MJ, Samant RS, Verderame MF, Welch DR (Jun 2000). "Functional evidence for a novel human breast carcinoma metastasis suppressor, BRMS1, encoded at chromosome 11q13". Cancer Res. 60 (11): 2764-9. 2. "Entrez Gene: BRMS1 breast cancer metastasis suppressor 1".

    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Antigène

    BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))

    Autre désignation

    BRMS1

    Sujet

    Synonyms: Breast cancer metastasis-suppressor 1,BRMS1,

    Tissue Specificity: Expression levels are higher in term placentas than in early placentas. Low levels of expression observed in normal pregnancies and in molar pregnancies. .

    Background: Breast cancer metastasis-suppressor 1 is a protein that in humans is encoded by the BRMS1 gene. This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.

    Poids moléculaire

    34 kDa

    ID gène

    25855
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