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IGFBPI anticorps (AA 69-259)

IGFBPI Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5518851
  • Antigène Voir toutes IGFBPI Anticorps
    IGFBPI (Insulin-Like Growth Factor Binding Protein 1 (IGFBPI))
    Épitope
    • 12
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 69-259
    Reactivité
    • 60
    • 32
    • 12
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 61
    • 13
    • 4
    • 2
    Lapin
    Clonalité
    • 64
    • 16
    Polyclonal
    Conjugué
    • 44
    • 10
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Cet anticorp IGFBPI est non-conjugé
    Application
    • 53
    • 33
    • 23
    • 9
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Fonction
    Rabbit IgG polyclonal antibody for Insulin-like growth factor-binding protein 1(IGFBP1) detection. Tested with WB, IHC-P in Human.
    Réactivité croisée (Details)
    No cross reactivity with other proteins.
    Attributs du produit
    Rabbit IgG polyclonal antibody for Insulin-like growth factor-binding protein 1(IGFBP1) detection. Tested with WB, IHC-P in Human.
    Gene Name: insulin-like growth factor binding protein 1
    Protein Name: Insulin-like growth factor-binding protein 1
    Purification
    Immunogen affinity purified.
    Immunogène
    E.coli-derived human IGFBP1 recombinant protein (Position: A69-N259). Human IGFBP1 shares 67.8% and 69.3% amino acid (aa) sequence identity with mouse and rat IGFBP1, respectively.
    Isotype
    IgG
    Top Product
    Discover our top product IGFBPI Anticorps primaire
  • Indications d'application
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Antigène
    IGFBPI (Insulin-Like Growth Factor Binding Protein 1 (IGFBPI))
    Autre désignation
    IGFBP1 (IGFBPI Produits)
    Synonymes
    anticorps cb656, anticorps igfbp1, anticorps IGFBP-1, anticorps MGC68538, anticorps afbp, anticorps ibp1, anticorps pp12, anticorps igf-bp25, anticorps higfbp-1, anticorps IGFBP1, anticorps LOC100223208, anticorps LOC100305121, anticorps AFBP, anticorps IBP1, anticorps IGF-BP25, anticorps PP12, anticorps hIGFBP-1, anticorps IGFBA, anticorps insulin like growth factor binding protein 1, anticorps insulin-like growth factor binding protein 1a, anticorps insulin like growth factor binding protein 1 S homeolog, anticorps insulin like growth factor binding protein 1 L homeolog, anticorps insulin-like growth factor binding protein 1, anticorps IGFBP1, anticorps igfbp1a, anticorps igfbp1.S, anticorps igfbp1.L, anticorps igfbp1, anticorps LOC100305121, anticorps Igfbp1
    Sujet
    IGFBP1, Insulin-like growth factor-binding protein 1, also known as placental protein 12 (PP12), is a protein that in humans is encoded by the IGFBP1 gene. The IGFBP1 gene has 4 exons and spans 5.9 kb. And the IGFBP1 gene is localized to 7p13-p12 by in situ hybridization. This gene is a member of the Insulin-like growth factor-binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a type-I thyroglobulin domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

    Synonyms: Insulin-like growth factor-binding protein 1 | IBP-1 | IGF-binding protein 1 | IGFBP-1 | Igfbp1 | Igfbp-1 | P08833
    ID gène
    3484
    UniProt
    P08833
    Pathways
    Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Growth Factor Binding
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