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HOXB1 anticorps (C-Term)

Cet anticorps anti-HOXB1 est un anticorps Lapin Polyclonal détectant HOXB1 dans WB. Adapté pour Humain, Souris et Rat.
N° du produit ABIN5518919

Aperçu rapide pour HOXB1 anticorps (C-Term) (ABIN5518919)

Antigène

Voir toutes HOXB1 Anticorps
HOXB1 (Homeobox B1 (HOXB1))

Reactivité

  • 30
  • 24
  • 9
  • 6
  • 6
  • 5
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Humain, Souris, Rat

Hôte

  • 37
  • 3
Lapin

Clonalité

  • 38
  • 2
Polyclonal

Conjugué

  • 28
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp HOXB1 est non-conjugé

Application

  • 32
  • 16
  • 3
  • 2
  • 2
Western Blotting (WB)
  • Épitope

    • 8
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 176-220, C-Term

    Fonction

    Anti-HOXB1 Antibody Picoband®

    Séquence

    TARTFDWMKV KRNPPKTAKV SEPGLGSPSG LRTNFTTRQL TELEK

    Réactivité croisée (Details)

    No cross-reactivity with other proteins.

    Attributs du produit

    Anti-HOXB1 Antibody Picoband® (ABIN5518919). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Purification

    Immunogen affinity purified.

    Immunogène

    A synthetic peptide corresponding to a sequence at the C-terminus of human HOXB1, different from the related mouse sequence by four amino acids.

    Isotype

    IgG
  • Indications d'application

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    1. Iimura, T., Pourquie, O. Collinear activation of Hoxb genes during gastrulation is linked to mesoderm cell ingression. Nature 442: 568-571, 2006. 2. Goddard, J. M., Rossel, M., Manley, N. R., Capecchi, M. R. Mice with targeted disruption of Hoxb-1 fail to form the motor nucleus of the VIIth nerve. Development 122: 3217-3228, 1996. 3. Webb, B. D., Shaaban, S., Gaspar, H., Cunha, L. F., Schubert, C. R., Hao, K., Robson, C. D., Chan, W.-M., Andrews, C., MacKinnon, S., Oystreck, D. T., Hunter, D. G., Iacovelli, A. J., Ye, X., Camminady, A., Engle, E. C., Jabs, E. W. HOXB1 founder mutation in humans recapitulates the phenotype of Hoxb1-/- mice. Am. J. Hum. Genet. 91: 171-179, 2012.

    Commentaires

    We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Antigène

    HOXB1 (Homeobox B1 (HOXB1))

    Autre désignation

    HOXB1

    Sujet

    Synonyms: Homeobox protein Hox-B1,Homeobox protein Hox-2I,HOXB1,HOX2I,

    Background: Homeobox protein Hox-B1 is a protein that in humans is encoded by the HOXB1 gene. This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXB genes located in a cluster on chromosome 17.

    Poids moléculaire

    32 kDa

    ID gène

    3211

    UniProt

    P14653
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