MED14 anticorps (AA 181-375)

N° du produit ABIN5519034

Détail du produit anti-MED14 anticorps

Antigène: MED14 (Mediator Complex Subunit 14 (MED14))

Épitope: AA 181-375

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MED14 est non-conjugé

Application: Western Blotting (WB), ELISA

Fonction: Rabbit IgG polyclonal antibody for MED14 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for MED14 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.
Gene Name: mediator complex subunit 14
Protein Name: Mediator of RNA polymerase II transcription subunit 14

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived huamn MED14 recombinant protein (Position: D181-D375).

Isotype: IgG

Information d'application

Indications d'application: Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur MED14

Antigène: MED14 (Mediator Complex Subunit 14 (MED14))

Autre désignation: MED14 (MED14 Produits)

Synonymes: anticorps CG12031, anticorps Dmel\\CG12031, anticorps Med14, anticorps Trap170, anticorps dTRAP170, anticorps p160, anticorps EXLM1, anticorps crsp150, anticorps crsp2, anticorps trap170, anticorps wu:fd21c05, anticorps wu:fk28h11, anticorps CRSP2, anticorps NV18605, anticorps CRSP150, anticorps CSRP, anticorps CXorf4, anticorps DRIP150, anticorps RGR1, anticorps TRAP170, anticorps 9930001L01Rik, anticorps AU041628, anticorps Crsp2, anticorps ENSMUSG00000073278, anticorps Gm641, anticorps ORF1, anticorps RGD1560170, anticorps Mediator complex subunit 14, anticorps mediator complex subunit 14, anticorps mediator of RNA polymerase II transcription subunit 14, anticorps transcriptional regulation, anticorps MED14, anticorps med14, anticorps LOC100113592, anticorps Med14, anticorps RGR1

Sujet: Mediator of RNA polymerase II transcription subunit 14 is an enzyme that in humans is encoded by the MED14 gene. The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation.

Synonyms: Mediator of RNA polymerase II transcription subunit 14, Activator-recruited cofactor 150 kDa component, ARC150, Cofactor required for Sp1 transcriptional activation subunit 2, CRSP complex subunit 2, Mediator complex subunit 14, RGR1 homolog, hRGR1, Thyroid hormone receptor-associated protein complex 170 kDa component, Trap170, Transcriptional coactivator CRSP150, Vitamin D3 receptor-interacting protein complex 150 kDa component, DRIP150, MED14, ARC150, CRSP2, CXorf4, DRIP150, EXLM1, RGR1, TRAP170

ID gène: 9282

UniProt: O60244

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha